Amoksisilinina

Amoksisilinina
Clinical data
Pronunciation	Endrika:IPAc-en
Trade names	Hundreds of names
Anarana hafa	Endrika:Infobox drug/localINNvariants
AHFS/Drugs.com	Monograph
MedlinePlus	a685001
[[Regulation of therapeutic goods \|Endrika:Engvar data]]	US DailyMed: Amoxicillin;
Pregnancy; category	AU: A;
Routes of; administration	By mouth, intravenous
Drug class	β-lactam antibiotic
Sata ara-dalàna
Sata ara-dalàna	UK: POM (Prescription only); US: ℞-only; In general: ℞ (Prescription only);
Pharmacokinetic data
Bioavailability	95% by mouth
Metabolism	less than 30% biotransformed in liver
Elimination half-life	61.3 minutes
Excretion	Kidneys
Identifiers
	IUPAC name (2S,5R,6R)-6-{[(2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid ;
Angon-drakitra simika sy ara-batana
Raikipohy	C16H19N3O5S
Molar mass	36540 g·mol−1
Modely 3D (JSmol)	Interactive image;
Density	1.6±0.1 g/cm3
	SMILES O=C(O)[C@@H]2N3C(=O)[C@@H](NC(=O)[C@@H](c1ccc(O)cc1)N)[C@H]3SC2(C)C ;
	InChI InChI=1S/C16H19N3O5S/c1-16(2)11(15(23)24)19-13(22)10(14(19)25-16)18-12(21)9(17)7-3-5-8(20)6-4-7/h3-6,9-11,14,20H,17H2,1-2H3,(H,18,21)(H,23,24)/t9-,10-,11+,14-/m1/s1 ; Key:LSQZJLSUYDQPKJ-NJBDSQKTSA-N ;
	(verify)

Antibiotika ampiasaina hitsaboana aretina bakteria maromaro ny Amoxicillin.^[3] Anisan'izany ny aretin'ny sofina afovoany, ny aretin'ny tenda, ny pnemonia, ny aretin'ny hoditra, ary ny aretin'ny lalan-drà.^[4]^[3] Atelina izy io, na tsy dia matetika amin'ny alalan'ny tsindrona.^[3]^[5]

Anisan'ny voka-dratsy mahazatra ny maloiloy sy ny mangidihidy.^[3] Mety hampitombo ny mety hisian'ny aretin'ny leviora ihany koa izany, ary rehefa ampiasaina miaraka amin'ny asidra clavulanic, dia miteraka aretim-pivalanana.^[6] Tsy tokony hampiasaina amin'ireo izay tsy mahazaka penisilinina izy io.^[3] Na dia azo ampiasaina amin'ireo manana olana amin'ny voa aza, dia mety mila ahena ny fatrany.^[3] Toa tsy mampidi-doza ny fampiasana azy mandritra ny fitondrana vohoka sy ny fampinonoana.^[3] Ao amin'ny fianakavian'ny antibiotika beta-lactam ny Amoxicillin.^[3]

Hita tamin'ny 1958 ny Amoxicillin ary nanomboka nampiasaina ara-pitsaboana tamin'ny 1972.^[7]^[8] Ao amin'ny lisitry ny fanafody tena ilaina ao amin'ny Fikambanana Iraisam-pirenena Momba ny Fahasalamana izany.^[9] Iray amin'ireo antibiotika matetika indrindra omena ny ankizy izy io.^[10] Azo vidiana ho fanafody tsy misy fangarony ny Amoxicillin ary tsy dia lafo loatra.^[3]^[11] Tamin'ny taona 2017, io no fanafody faha-18 be mpampiasa indrindra any Etazonia, miaraka amin'ny fanafody mihoatra ny 27 tapitrisa.^[12]^[13]

References

↑ "International brand names for amoxicillin". www.drugs.com. Drugs.com. Archived from the original on 29 May 2016. Retrieved 15 November 2016. Endrika:Webarchive
↑ "Amoxicillin". www.chemsrc.com. Archived from the original on 2017-05-19. Retrieved 2018-05-08. Endrika:Webarchive
1 2 3 4 5 6 7 8 9 "Amoxicillin". The American Society of Health-System Pharmacists. Archived from the original on 5 September 2015. Retrieved 1 August 2015."Amoxicillin".
↑ Ritter, James M. (2024). “52. Antibacterial drugs”, Rang & Dale's Pharmacology, 10th (in English), Elsevier.
↑ "Amoxicillin Sodium for Injection". EMC. 10 February 2016. Archived from the original on 27 October 2016. Retrieved 26 October 2016.
↑ Gillies, M; Ranakusuma, A; Hoffmann, T; Thorning, S; McGuire, T; Glasziou, P; Del Mar, C (17 November 2014). "Common harms from amoxicillin: a systematic review and meta-analysis of randomized placebo-controlled trials for any indication". CMAJ : Canadian Medical Association Journal 187 (1): E21–31. doi:10.1503/cmaj.140848. PMC 4284189. PMID 25404399. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4284189.
↑ Fischer, Janos (2006). Analogue-based Drug Discovery (in en). John Wiley & Sons.
↑ Roy, Jiben (2012). An introduction to pharmaceutical sciences production, chemistry, techniques and technology. Cambridge: Woodhead Pub..
↑ (2019) World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
↑ Kelly, Deirdre (2008). Diseases of the liver and biliary system in children, 3, Chichester, UK: Wiley-Blackwell.
↑ Hanno, Philip M. (2014). Penn Clinical Manual of Urology E-Book (in en). Elsevier Health Sciences.
↑ "The Top 300 of 2020". ClinCalc. Archived from the original on 18 March 2020. Retrieved 11 April 2020.
↑ "Amoxicillin Drug Usage Statistics". ClinCalc. 1 December 1981. Archived from the original on 11 April 2020. Retrieved 11 April 2020.

[brands-1] "International brand names for amoxicillin". www.drugs.com. Drugs.com. Archived from the original on 29 May 2016. Retrieved 15 November 2016. Endrika:Webarchive

[chemsrc-2] "Amoxicillin". www.chemsrc.com. Archived from the original on 2017-05-19. Retrieved 2018-05-08. Endrika:Webarchive

[AHFS2015-3] 1 2 3 4 5 6 7 8 9 "Amoxicillin". The American Society of Health-System Pharmacists. Archived from the original on 5 September 2015. Retrieved 1 August 2015."Amoxicillin".

[Ritter-4] Ritter, James M. (2024). “52. Antibacterial drugs”, Rang & Dale's Pharmacology, 10th (in English), Elsevier.

[5] "Amoxicillin Sodium for Injection". EMC. 10 February 2016. Archived from the original on 27 October 2016. Retrieved 26 October 2016.

[6] Gillies, M; Ranakusuma, A; Hoffmann, T; Thorning, S; McGuire, T; Glasziou, P; Del Mar, C (17 November 2014). "Common harms from amoxicillin: a systematic review and meta-analysis of randomized placebo-controlled trials for any indication". CMAJ : Canadian Medical Association Journal 187 (1): E21–31. doi:10.1503/cmaj.140848. PMC 4284189. PMID 25404399. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4284189.

[7] Fischer, Janos (2006). Analogue-based Drug Discovery (in en). John Wiley & Sons.

[8] Roy, Jiben (2012). An introduction to pharmaceutical sciences production, chemistry, techniques and technology. Cambridge: Woodhead Pub..

[WHO21st-9] (2019) World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.

[10] Kelly, Deirdre (2008). Diseases of the liver and biliary system in children, 3, Chichester, UK: Wiley-Blackwell.

[Hanno2014-11] Hanno, Philip M. (2014). Penn Clinical Manual of Urology E-Book (in en). Elsevier Health Sciences.

[ref-12] "The Top 300 of 2020". ClinCalc. Archived from the original on 18 March 2020. Retrieved 11 April 2020.

[ref1-13] "Amoxicillin Drug Usage Statistics". ClinCalc. 1 December 1981. Archived from the original on 11 April 2020. Retrieved 11 April 2020.

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

[9]

[10]

[11]

[12]

[13]